Recent Approaches in Magnetic Nanoparticle-Based Biosensors of miRNA Detection

In recent years, magnetic nanoparticles (MNPs) have been widely used in many fields due to their advantageous properties, such as biocompatibility, easy modifiability, and high chemical stability. One of these areas is the detection cancer. It essential use existing biomarkers, microRNAs (miRNAs), for early diagnosis this disease. miRNAs are challenging distinguish detect biological samples because they small, circulating molecules. necessary more sensitive feature-rich systems. Thanks large surface moments, MNPs allow separation miRNA at low concentrations from complex (urine blood) rapid specific biosensing Here, we discussed synthesis characterization methods MNPs, stabilization, MNP-based biosensors terms detection. We considered challenges prospects biosensor systems evaluating development stages, sensitivity, selectivity.